The effect of Enamel Matrix Proteins on the periodontal tissue and cells and periodontal regeneration was reviewed. 兹就釉基质蛋白对牙周组织和细胞的作用及其在牙周组织再生方面的研究概况加以综述。
Effects of enamel matrix proteins loaded in chitosan thermosensitive hydrogel on bone marrow stromal cells in vitro 壳聚糖温敏凝胶负载釉基质蛋白对骨髓基质细胞的作用
Effects of enamel matrix proteins on synthesizing collagen type ⅰ and type ⅲ of SD rats ′ marrow stroma cells in vitro 釉基质蛋白对大鼠骨髓基质细胞合成Ⅰ、Ⅲ型胶原的影响
AIM: To explore a simple approach to the isolation and purification of rat enamel organ cells. 目的:寻找一种大鼠成釉器细胞分离纯化的简捷方法。
Effects of enamel matrix proteins on the attachment, spreading and proliferation of porcine bone marrow stromal cells in vitro 釉基质蛋白对猪骨髓基质细胞黏附、伸展及增殖的影响
Objective To investigate the expression of BMP-2 in mice incisor enamel organ cells under chronic fluoride exposure and elucidate the mechanism of dental fluorosis. 目的观察慢性氟中毒对小鼠切牙成釉细胞骨形成蛋白-2(BMP-2)表达的影响,探讨氟斑牙的致病机制。
Results The expression of BMP was seen primarily in enamel organ cells. 结果BMP的表达主要在造釉器。
Objective To evaluate the effect of enamel matrix protein ( EMP) on the attachment and proliferation of periodontal ligament cells ( PDLC) on diseased cementum surfaces in vitro. 目的观察釉基质蛋白(EMP)对牙周膜细胞(PDLC)在牙周炎患牙牙骨质根面上附着和增殖的影响。
In bell stage ( E19), the positive staining was detected in both inner and outer enamel epithelium, but the inner was less than that of the outer and less positive staining was also found in the cells of stratum intermedium and stellate reticulum. 钟状期(胚胎19d),内、外釉上皮阳性表达,但内釉上皮较外釉上皮表达弱,中间层及星网状层细胞弱阳性表达;
Methods A dental fluorosis mouse model was established. The expression of BMP-2 in enamel organ cells of the mice mandibular incisor was examined by using SABC immunohistochemistry. 方法建立小鼠慢性氟中毒氟斑牙模型,SABC免疫组化法检测下切牙成釉器细胞内BMP-2的表达分布。
CONCLUSION: Purified enamel organ cells can be obtained by repeated differential digestion. 结论:本研究通过多次差别消化获得了纯化的大鼠成釉器细胞。
CONCLUSION: At onset of HERS, the inner enamel epithelium, outer enamel epithelium embrace several cells with developed cytoplasmic organelles, which may derive from stratum intermedium or stellate reticulum, and form a structure like enamel organ, which may be associated with initial cementogenesis. 结论:上皮根鞘发生时,内、外釉上皮间可包容个别源于网状层或中间层、细胞器丰富的细胞,从而形成类似成釉器的结构。
Conclusion Fluoride in enamel organ cells inhibited the expression of BMP-2 and impaired the secretion of enamel. 结论氟抑制BMP-2在成釉细胞中的表达,影响釉基质分泌。
Conclusion: EMPs are not osteoinductive. Effects of Enamel Matrix Proteins on the Biological Activity of Porcine Bone Marrow Stromal Cells in Vitro 结论:提取的猪釉基质蛋白未具有骨诱导作用。釉基质蛋白对猪骨髓基质细胞生物学特性的影响
Isolation and purification of rat enamel organ cells 大鼠成釉器细胞的分离纯化
BMP may also be found in human tooth germs, predentin, the cells of outer and inner enamel epithelium, and the cells of dental sac generating alveolar bone. 在人的牙胚中,BMP主要分布在前期牙木质、外釉细胞和造釉细胞以及形成牙槽骨的牙囊细胞中,表明骨的生长和形成以及牙齿的发育都与BMR密切相关。
Objective To prepare enamel matrix proteins ( EMPs) loaded dextran-based hydrogel microspheres ( EMPs-dex-MPs), and to evaluate their EMPs controlled release property and their biological effects on the proliferation and differentiation of human periodontal ligament cells ( PDLCs) in vitro. 目的探讨载釉基质蛋白(EMPs)的右旋糖酐基凝胶微球(dexMPs)的制备工艺及其理化与生物学性能。
Dental enamel is formed by dental epithelial cells, while dentin-pulp complex is generated by the mesenchymal cells around them. 其中,牙釉质是由牙胚发育早期的牙源性上皮细胞形成的,而牙本质牙髓复合体则是由其周围的牙源性间充质细胞所形成。
Effects of enamel matrix proteins on transforming growth factor β 1 releasing from SD rat bone marrow stroma cells in vitro 釉基质蛋白对骨髓基质细胞分泌TGF-β1的影响
It was found that apical bud and incisor papilla cells pellet developed into well-formed enamel and dentin tissues, whereas the combination of HERS cells and molar papilla cells produced bone-like dentin tissues. 结果发现:Apicalbud和切牙牙乳头细胞团形成组织结构规则的釉质和牙本质组织,HERS细胞与磨牙牙乳头细胞团形成了骨样牙本质样组织。